What does global health mean at the beginning of the 21st century? What is it aiming to do? What does it mean in terms of practice and the way that we understand things? Let's take the example of malaria. Nearly 500,000 deaths and more than 200 million cases should not be occurring, for the very reason that malaria is an easy disease to prevent. This is a scandal. We have no choice but to solve this major global health crisis.